The men's quadruple sculls competition at the 2000 Summer Olympics in Sydney, Australia took place at the Sydney International Regatta Centre.

The "scull" portion means that each rower uses two oars, one on each side of the boat; this contrasts with sweep rowing in which each rower has one oar and rows on only one side.

All other boats progress to the repechage round, which offers a second chance to qualify for the semi-finals.

The best three boats in each of the two semi-finals qualify for final A, which determines places 1–6 (including the medals).

Unsuccessful boats from semi-finals A/B go forward to final B, which determines places 7–12.