Roxanne Vincenta Modafferi[1] (born September 24, 1982) is an American retired mixed martial artist, who most recently fought for the UFC.

[9] Modafferi's training began in Taekwondo at the age of 13 in Pennsylvania, moving on to Mark Lawler's Kenpō Karate in the high school.

She trained for three years to gain a brown belt in the style, and then graduated from Lenox Memorial High School.

In addition, she trained at another Royce Gracie association in Hartford, Connecticut, for about a year (necessitating a weekly two-hour round trip), also investigating Jeremy Libiszewski's School of Self-Defence in Wilbraham, Massachusetts.

During summer vacations in Boston, she trained at Joao Amaral's New England BJJ club, now associated with Brazilian Top Team.

To work on her striking, she also attended the Sityodtong Muay Thai Academy's North American branch in Somerville, Massachusetts, run by Kru Mark DellaGrotte.

She achieved a 3–0 mixed martial arts record in the Smackgirl promotion and defeated Jennifer Howe.

[citation needed] After graduating in May 2005, she secured a position with Berlitz, teaching English in Japan and arriving for the second time in July 2005.

Modafferi earned a win by split decision against Cassandra Rivers-Blasso at Fatal Femmes Fighting on February 2, 2007.

She became K-GRACE Women's Open-Weight Tournament Champion by defeating Hee Jin Lee, Megumi Yabushita and Marloes Coenen on May 27, 2007.

[17] On January 30, 2010, Modafferi submitted Molly Helsel in the second round at King of the Cage: Toryumon in Okinawa, Japan.

[30] Modafferi was scheduled to face Aisling Daly at BlackEye Promotions 5 in Fletcher, North Carolina, on October 1, 2011.

[38] In the elimination fight to get into the TUF house, Modafferi faced Valérie Létourneau and won via a rear-naked choke submission in the first round.

Modafferi faced Mariana Morais at Invicta FC 14: Evinger vs. Kianzad on Saturday, September 12, 2015, and won via TKO stoppage in the third round.

[43] Modafferi was scheduled to face fellow semifinalist Barb Honchak on December 1, 2017, at The Ultimate Fighter 26 Finale.

[44] However, on the day of the weigh in, Sijara Eubanks was pulled from the fight for kidney failure and was replaced by Modafferi to face Nicco Montaño for the Flyweight title.

[55] The victory earned Modafferi the distinction of being the first female UFC fighter to win a bout in Russia.

[57] However, Carmouche was pulled from that bout in favor of a rematch with current champion Valentina Shevchenko in August at UFC Fight Night 156.

[73] However, Suarez was pulled from the event due to injury,[74] and she was replaced by Taila Santos[75] She lost the fight via unanimous decision.

[82] On October 25, 2020, Modafferi faced Danielle Kelly in the main event of Submission Hunter Pro 60 for the inaugural 130lbs no gi title and was submitted with a toehold.

[83] Modafferi was given the opportunity to challenge Amanda Loewen for the SUG absolute title at Submission Underground 21 on March 28, 2021.

[85] Modafferi faced Michele Oliveira in a superfight at UFC Fightpass Invitational 2 on July 3, 2022, and lost a decision.

[86] Modafferri writes a regular column titled Dear Roxy for MMA website Bloody Elbow.