Roy C. Start (November 3, 1877 – December 15, 1956), born in Holmes Township, Ohio, was the Republican mayor of Toledo from 1936–40.

After college he moved to Toledo where he served as a clerk in a drug store owned by Paul Loesser.

A year later, in 1902, he opened his own drug store on the corner of Franklin Avenue and Cherry Street in Toledo.

He was a member of several civic and masonic organizations, including the Barton Smith Lodge F&AM, Collingwood Chapel, Scottish Rite, Zenobia Shrine, West Toledo Exchange Club, West Toledo Commerce Club, Municipal League, Ohio Congregational Church Union, Lucas County Pharmaceutical Association.

Gilbert Siegel a Republican running for Mayor of Toledo and also a drug store owner like Start, was quoted as saying, "Yes Sir...

"[5] This was more than 12 years after Start had died, proof that his legacy was lasting in the Toledo and Northwest Ohio area.