[3] Dotrice was the voice of "Permanent Under-Secretary Sir Gregory Pitkin" in the early episodes of BBC Radio's long-running comedy The Men from the Ministry.

[7] These runs, combined with extensive international touring, earned Dotrice a place in the Guinness World Records for the greatest number of solo performances (1,782).

[9] He appeared in the stage production of Irving Berlin's White Christmas at The Lowry theatre in Salford from November 2009 to January 2010.

His acting career dates from 1945 in a revue called Back Home, performed by former prisoners-of-war in aid of the Red Cross.

[9] In June 2010 it was announced that Dotrice would be playing the role of Grand Maester Pycelle in the HBO television series Game of Thrones, an adaptation of George R. R. Martin's A Song of Ice and Fire books.

[11] Shortly after filming for the second season commenced it was confirmed that Dotrice would be returning to play "Wisdom Hallyne the Pyromancer",[12] who is featured in the installments "The Ghost of Harrenhal" and "Blackwater".

[14] He subsequently performed "The Islander", a stage version of The Book of Ebenezer Le Page, to critical success at the Theatre Royal Lincoln.

[13][16][17] Dotrice also narrated many storybook adaptations for Disney Records, including The Little Mermaid and Pooh's Heffalump Movie, for which he was nominated for a Grammy Award.