Roy Isao Sano (born 1931) is a retired Japanese-American bishop of the United Methodist Church, elected in 1984.
Sano was born on 18 June 1931 in Brawley, California, of Japanese immigrants to the United States.
Sano completed his undergraduate studies at the University of California at Los Angeles, majoring in American history.
While in seminary he served as minister of education for the Japanese-American congregation of the United Church of Christ in New York City.
In 1969 Sano became the chaplain and an assistant professor of religion at Mills College, positions he held until 1976.
He served as executive secretary of the Council of Bishops of The United Methodist Church in Washington, D.C. from 2004 to 2008.