The Royal Scot was a named passenger express train that ran between London Euston and Glasgow Central on the West Coast Main Line (WCML), with previously a portion also going to Edinburgh.

For many years it departed from both ends at 10:00 (mirroring the Flying Scotsman on the East Coast Main Line).

On 11 July 1927, the London Midland and Scottish Railway (LMS) relaunched the service under a new name, the Royal Scot.

[1] In August 1927, the LMS introduced the modern and more powerful Royal Scot Class, a series of 4-6-0 locomotives that took over the service and ran from London Euston and Carlisle non-stop.

Instead, London-Glasgow now has an hourly service of British Rail Class 390 Pendolino units operated by Avanti West Coast with a standard overall journey time of 4 hours 31 minutes, running non-stop between London and Warrington Bank Quay.