Rubén Aguirre was born on 15 June 1934 in the neighborhood of Santa Anita located at Saltillo, Coahuila, Mexico.

[5] In his book Después de Usted (After You, a common phrase used by his character Professor Jirafales), published in February 2015, he wrote about the difficulty of finding higher education institutions in Mexico during the mid 1950s, since there were very few schools.

He returned to Juárez and began working as a radio host; he married his wife Consuelo de los Reyes, whom he met at a bullfight, finished his degree in Agricultural Engineering with a minor in Mechanized Systems and some time after he moved to Monterrey, Nuevo León, where he began his acting career and met Roberto Gómez Bolaños.

[7] Nevertheless, despite his height, he was able to begin his acting career in Monterrey, Nuevo León, working with a character named Pipo, a famous clown.

His acting caught the eye of Mexican producer Roberto Gómez Bolaños who asked him to work with him in Mexico City.