Ruby Butler DeMesme (June 24, 1948 – April 20, 2020)[1] was United States Assistant Secretary of the Air Force for Manpower, Reserve Affairs, Installations and Environment from 1998 to 2001.

[2] From 1969 to 1980, DeMesme worked as an executive administrator in the Cumberland County, North Carolina Department of Social Services.

[2] In 1980, she joined the United States Department of the Army and spent the next decade working in a number of positions dealing with personnel.

[2] On July 6, 1998, President of the United States Bill Clinton announced his intent to nominate DeMesme to be Assistant Secretary of the Air Force for Manpower, Reserve Affairs, Installations and Environment.

[4] After her 2020 death in Myrtle Beach, South Carolina,[1] DeMesme was interred at Arlington National Cemetery on June 12, 2020.