10 and 12 are built on the former location of another prominent mansion, which in the 14th century belonged to the Counts of Artois, thus known as the Hôtel d'Arras, with main entrance at what is now no.

A bookshop affiliated with the Maoist Union des jeunesses communistes marxistes-léninistes operated at no.

6 from 1967 to 1978, bankrolled by the wealthy grandmother of activist Tiennot Grumbach [fr],[7] and gave its name to the short-lived far-left publishing house Editions Gît-le-Cœur.

A trade association of sellers of ancient books, the Syndicat de la Librairie Ancienne et Moderne, has been located at no.

6, a fencing club (salle d'armes) opened in 1886 and still operates as of 2022, claiming to be the oldest remaining in Paris.

[11] As of 2021, the tiny street's commercial activity is mainly related to tourism, with several hotels and restaurants.

Like other atmospheric streets of the Latin Quarter, the Rue Gît-le-Cœur has inspired works by artists including Charles Marville,[20] Bram van Velde,[21] and Roger Vieillard [fr].