The House of Ruffo di Calabria is the name of an ancient, one of the most prominent and longest-standing Italian noble families.

[1] It was already one of the seven most important houses of the Kingdom of Naples.

[2] Their most notable members include Rembrandt's patron Antonio Ruffo, Russian princess Elisabetta di Sasso Ruffo, the flying ace Prince Fulco Ruffo di Calabria and his daughter Donna Paola Ruffo di Calabria, who became Queen Paola of Belgium the spouse of King Albert II of Belgium.