[9] This popularity has led to many after-market modifications being available to improve performance, augment the rifle's looks, or increase its magazine capacity, making the 10/22 one of the most customizable firearms ever made.

[10][11] Custom manufacturers also make "clones" of the 10/22, which are similar in design (most parts will interchange) but built to much higher specifications and costs.

This allows the magazine to be compact and fit flush into the rifle without protruding from the stock at the natural balance point for one-handed carry.

The 10/22 Competition rifle has a hard-coat anodized, CNC-machined receiver made from heat-treated and stress relieved 6061-T6511 aluminum.

The receiver incorporates a rear cleaning port and an integral, optics-ready 30 MOA Picatinny rail.

The rifle also has an enhanced semi-auto chamber, BX-Trigger, heat-treated and nitrided CNC-machined match bolt, 16-1/8" cold hammer-forged bull free-floating barrel which is fluted to reduce weight and dissipate heat and is also threaded with a 1/2"-28 pattern to accommodate the included muzzle brake or other barrel accessories.

It had a black alloy receiver with "1964-2014" special markings, 18.5" barrel, fiber optic sights, and a 25-round magazine.

It features a dark grey version of Ruger's Modular Stock System found on the Ruger American Rimfire rifle, a protected non-glare blade front sight, ghost ring adjustable rear aperture sight, and a Picatinny rail.

It is equipped with a Magpul Hunter X-22 polymer stock with an ergonomic grip, adjustable length of pull and comb height, multiple sling mounting options, a non-slip rubber buttpad, and M-LOK slots for accessory attachment.

[21][22] The standard Takedown model has a brushed aluminum receiver made to resemble stainless steel and 18.5" barrel with a black synthetic stock.

The SR-22 rifle boasts an aluminium handguard, adjustable six position stock, and a top receiver rail.

The 22 Charger originally came with a black laminated wood pistol stock with forend, a 10-inch (254 mm) matte blued heavy barrel, a bipod, and a Weaver style scope base in lieu of iron sights.

[24][25] It was reintroduced in December 2014, with a brown laminate stock with a M16A2 style pistol grip, 10-inch threaded barrel, picatinny rail, 15-round magazine and adjustable bipod.

[27] A wide variety of aftermarket modification kits are offered for the 10/22, including conversions to bullpup configuration and cosmetic alterations to replicate the appearance of weapons like the M1 Carbine, Thompson submachine gun, FN P90, and AR-15.

Due to the integral suppressor, this model is a Title II weapon in the U.S.[28] The AT 10/22 QD is a short-barreled modified version of the 10/22 made by Arms Tech Limited.

It features a six-inch barrel, a folding stock, and is designed to accept Arms Tech's own QD-223 suppressor.

Due to its extremely short barrel, it is considered a Title II weapon in the U.S.[29] The Thompson/Center T/CR22 is a .22 LR-caliber clone of the Ruger 10/22 semi-automatic rifle manufactured by Thompson/Center Arms.