It was made stronger with the intent to fire an unlimited number of full-power .357 Magnum rounds.

The first significant change was introduced with the Ruger Redhawk and that involved a new triple-locking cylinder mechanism with a lever on the crane rather than using the end of the ejector rod to lock.

The GP100 series, instead, used a small rectangular "peg" grip large enough to enclose the hammer spring and strut.

The stock grips are made of Santoprene, a soft, chemical resistant elastomer that helps absorb the recoil of firing.

All of these models use the same thickness on the solid frame and double latching system as used on the heavy .44 Magnum.

The transfer bar only assumes the required position when the trigger is pulled completely rearward.

[6] In 2021, Ruger produced 500 GP100s in memory of Jeff Quinn, a YouTuber and founder of the online firearms magazine Gunblast, who died the previous year.