The transfer bar safety allows the revolver to fire only when the trigger has been pulled.

Ruger provides the transfer bar safety upgrade free of charge for owners of any old model Single-Six,[8] though this may come with a significant trigger-feel penalty.

[9] The New Model Single-Six is currently chambered in .22 LR, .22 WMR (.22 Magnum), and .17 HMR (initially offered with a second cylinder in .17 HM2[10]).

The term Super Single-Six refers to those models which have fully adjustable target sights.

Both of these revolvers are stainless steel variants of the Single-Six design with fiber optic sights.