The Rusher Hotel, also known as the Great Southern Hotel, is a historic hotel building at 127 West Cedar Street in Brinkley, Arkansas.

It was built in 1915 to serve the Brinkley Union Station.

It is a three-story brick building, whose main entrance originally faced the railroad, but was reoriented to the street facade after the railroad declined in importance.

[2] The building was listed on the National Register of Historic Places in 1986,[1] and is a contributing property to the Lick Skillet Railroad Work Station Historic District.

This article about a property in Monroe County, Arkansas on the National Register of Historic Places is a stub.