[4] Fayfer made his professional debut on 30 August 2013, defeating Ukrainian rival Roman Mirzoev via unanimous decision (UD) in Blagoveshchenskaya, Russia.

Two years later, in July 2015, he took the Russian heavyweight title from prospect Vladimir Goncharov by way of majority decision (MD) in Moscow, giving the previously-undefeated fighter his first loss.

[5][6] Fayfer added seven more wins in 2016, capping the year off with a first-round knockout (KO) of former IBO world champion Fulgencio Zúñiga in Montpellier that improved his record as a pro to 18–0.

For his next fight, he matched up against Argentine veteran Cesar David Crenz in Saint Petersburg on 25 March 2017 for the vacant IBF International cruiserweight title.

[9] Fayfer suffered his first career defeat on 13 October 2018, losing by unanimous decision (116–111, 115–112, 114–113) to Andrew Tabiti in the cruiserweight quarter-finals of the 2018–19 World Boxing Super Series.