It is divided into nine bays, each measuring about 7 feet (2.1 m) (one sazhen) square, and covered by a hip roof.

The east and west ends of the building are further extended by shed-roof "galleries" that are 14 feet (4.3 m) wide, which historically provided space for stairwells, storage, latrines, and entrances.

The south facade was sheathed in clapboarding c. 1851, and the galleries were roofed in metal around that time.

The interior was repeatedly altered over the decades, and underwent a major restoration once the property was acquired by the National Park Service 1973.

[2] The property on which the Bishop's House stands includes two secondary buildings associated with the activities of the Russian Orthodox Church.

House 105, while not of architectural note, was used as a church rental property for many years, and is one of the oldest buildings in Sitka.