The Grahams have five children: Virginia (Gigi), Anne, Ruth, Franklin, and Nelson Edman (Ned), 19 grandchildren, and numerous great-grandchildren.

Her parents, Virginia Myers (née Leftwich) and Dr. L. Nelson Bell, were American medical missionaries at the Presbyterian Hospital 300 miles north of Shanghai.

[2] Between 1945 and 1958, Graham gave birth to five children, whom she raised – sometimes single-handedly – while her husband was away on extended national and international evangelistic crusades.

She went on to write or co-write 13 other books, many of them works of poetry she wrote as an emotional release while her husband was so often on the road through the years.

On June 13, 2007, following her decline into a semi-coma, her husband announced that he and his wife had decided to be buried beside each other at the Billy Graham Library in Charlotte, North Carolina.

EDT June 14, 2007, at the couple's home, Little Piney Cove, in Montreat, North Carolina, with her husband and five children at her bedside, four days after her 87th birthday.

[7] In a statement released from Wheaton College, Duane Litfin, president of the school, remarked, "Strong, steady, and dauntless, Ruth Bell Graham was the glue that held many of the parts of their lives together.

With Gigi Graham: Her biography, A Time for Remembering (later reissued as Ruth: A Portrait), was an early work of novelist Patricia Cornwell.