"Rx (Medicate)" is a song performed by Canadian rock band Theory of a Deadman, a track on their sixth studio album, Wake Up Call (2017).

The band's transition into the pop genre has been associated with lead singer Tyler Connolly's newly acquired piano-playing ability, which forced a change in his songwriting style.

"Rx (Medicate)" was released alongside its music video on July 27, 2017, as the lead single from Wake Up Call and served as an instant download on pre-orders of the album.

At live concerts, the band encourage their audience to seek help if they are battling addiction and invite their fans to share their personal stories.

[2] The song was recorded at Terefe's Kensaltown Studios in London and was mixed by Oskar Winberg, while engineering was done by George Murphy and Bobby Shin.

[10] Connolly said he wanted to be sure the lyrics did not convey the message that it is "cool to be high" or that the band were taking advantage or "poking fun" at issues surrounding substance abuse.

[11] Further inspiration came from Connolly's experience of seeking therapy following his divorce in 2010; he told Billboard, "...the first thing [the therapist] said was, 'I want to put you on some beta blockers or some sort of anti-depressant stuff' and I'm like, 'No!

[13][14] Classic Rock called the track "an atmospheric piece of acoustic pop-rock",[15] and Billboard and Loudwire both said it leans more towards the pop genre rather than the band's usual hard-rock sound.

[18] In less enthusiastic critiques of Wake Up Call, Über Röck's Jonni D criticized the single, stating that the "auto-tuned whistling hooks wreak aural havoc".

In the wake of the song's release, the band partnered with the nonprofit organization Shatterproof, to raise awareness about addiction and to form a connection with their fans.

Shatterproof focuses on removing the stigma often attached to drug and alcohol dependence and supports affected families and addicts in recovery and treatment programs.

Following live performances of "Rx (Medicate)", the organization's website is displayed on a large screen behind the band as they encourage others to seek help if they feel they are battling addiction.

Fans are invited to share their stories on faux prescription pads found at merchandise booths at the band's concerts and at Shatterproof's website.