[9][10] His father served as a lieutenant in the U.S. Army, in which his grandfather Henry Gene Skeen was a major general.

At age 16, while still attending high school, he won an internship at WSTR in Atlanta where Tom Sullivan trained him in many aspects of radio.

He appeared as the host of the fictional game show Lover's Lane on Beverly Hills, 90210 in "The Final Proof".

[16] During commercial breaks he offered trivia on the film and a chance to win prizes by answering online on NBCi.

[15][17] In 2002, Seacrest accepted the position as co-host of a new Fox reality television series American Idol with comedian Brian Dunkleman.

[22][23] In August 2005, it was announced that Seacrest would become executive producer and co-host of ABC's Dick Clark's New Year's Rockin' Eve.

On December 31, 2005, Seacrest performed much of the show's hosting duties; Dick Clark's role was limited by speech and mobility issues due to his recovery from a stroke.

[24] When Clark died, Seacrest publicly remembered his mentor's impact on his life in a special tribute in The Hollywood Reporter.

[33] Seacrest was an NBC correspondent for the 2012 London Olympic Games and co-hosted the closing ceremony with Bob Costas and Al Michaels.

[37] On February 16, 2023, Seacrest announced that he would be leaving Live with Kelly and Ryan after six years in April 2023, primarily due to traveling as his primary residence is in Los Angeles, while the show tapes in New York City.

Seacrest has stated, however, that he will return to guest host whenever Consuelos is unavailable, meaning he is not permanently leaving the show.

[39][40][41] On June 27, 2023, The New York Times reported that Seacrest would replace the outgoing Pat Sajak as the host of Wheel of Fortune beginning with the show's 42nd season in fall 2024, citing "two people familiar with the plan".

In August 2008, Seacrest named his longtime William Morris agent Adam Sher as CEO.

News and executive produces its red carpet awards show coverage but no longer hosts (since January 2012) E!

and Dick Clark's New Year's Rockin' Eve as springboards to a long-lasting career in television production and ownership.

RSP also produced the Emmy Award-winning ABC reality series Jamie Oliver's Food Revolution.

RSP also produced two new reality series in 2012 including Melissa and Tye, which aired on CMT and Shahs of Sunset for Bravo.

[62] On January 31, 2012, Thomas H. Lee Partners and Bain Capital announced they would invest up to $300M in Ryan Seacrest Media.

[63] A consortium headed by Seacrest (with partners AEG and CAA) agreed to rebrand Mark Cuban's HDNet television network as AXS TV.

The Typo keyboard was discontinued in a 2015 patent settlement with Blackberry Ltd.[68] He is also an investor and partner at Pathwater, a brand of purified water offered in a refillable aluminum bottle.

Seacrest wore close-fitting suits and decided to make something similar for a wider audience at an "accessible" price point.

It consists of suit separates, sports coats, and evening wear manufactured by Peerless Clothing International; accessories including ties, pocket squares, belts, wallets, cufflinks, and jewelry produced by Randa Accessories; and dress shirts from PVH (produced later by Itochu Prominent which added sportswear in September 2017).

[71][72][73] Seacrest partnered with dermatologist Harold Lancer to produce the men's skincare line Polished.

[87] Seacrest had a two-year on-and-off relationship with model Sara Jean Underwood, which was revealed on The Howard Stern Show in 2009.

[93][94] In May 2016, Seacrest returned to the University of Georgia to serve as the commencement speaker at the graduation ceremony and receive an honorary Doctor of Humane Letters.

[99] Seacrest denied the allegations and said, "This person who has accused me of horrible things offered, on multiple occasions, to withdraw her claims if I paid her millions of dollars.