He played in Major League Baseball (MLB) for the St. Louis Cardinals, Tampa Bay Rays, and Boston Red Sox.

In 2011 as a sophomore at Glendale Community College, he was named First Team All-Western State Conference South Division.

He was named to the 2016 Pacific Coast League All Star Team, while pitching for the Memphis Redbirds, and finished the 2016 season with a 7-1 record and 3 saves in 49 relief appearances, and a 2.84 ERA.

[12][13] The Washington Nationals selected Sherriff in the 33rd round of the 2010 Major League Baseball Draft from West Los Angeles College (Culver City), but he did not sign.

[28] Sherriff dropped his arm angle, relied on his sinker, and finished the 2016 season with a 7-1 record and 3 saves in 49 relief appearances (tied for second among Cardinals minor league pitchers), a 2.84 ERA, held left-handers to a .172 batting average, struck out 55 batters in 66.2 innings, and induced a very high percentage of ground balls (61%).

[33] At the time he joined one other Glendale alumnus in the major leagues, starting pitcher Marco Estrada of the Toronto Blue Jays.

[33] Two days later against the Tampa Bay Rays he became the first Cardinal since José Jiménez in 1998 to throw three scoreless innings in his major league debut.

[11] He held opposing left-handed hitters to a .080 batting average (2-25) with two singles, zero walks, and seven strikeouts, and a 65% ground ball rate.

[39] He underwent Tommy John surgery to reconstruct the ulnar collateral ligament in his left elbow on June 5, ending his season and likely sidelining him for at least 12 months.

[38] On August 26, 2020, the Rays selected Sherriff's contract to the active roster, replacing the injured Jalen Beeks.

[43] In the pandemic-shortened 2020 season, Sherriff was 1-0 with one save and a perfect 0.00 ERA, as in 10 relief appearances he pitched 9.2 scoreless innings and had an 0.828 WHIP, holding batters to a .188 batting average.

[44] After blowing a save in a 6-4 win against the Miami Marlins the previous day, on April 3, 2021, Sherriff was placed on the restricted list to "take some time away from the game.

Sherriff was shut down in late March due to biceps tendinitis, and was later transferred to the 60-day injured list on April 25, 2022.

[52] On August 1, Sherriff was designated for assignment but was not claimed by another team from waivers, thus remaining in the Phillies organization with the Triple-A Lehigh Valley IronPigs.

[54] On January 23, 2023, Sherriff signed a minor league contract with the Boston Red Sox organization.

[55] He began the year with the Triple-A Worcester Red Sox, making 15 appearances and working to a 3.00 ERA with 16 strikeouts in 15 innings pitched.

[53][59] On July 7, he was designated for assignment by the Red Sox after Yu Chang was activated from the injured list.

[63] In only two appearances in 1+2⁄3 innings of work for the Triple–A Oklahoma City Dodgers, as he was dealing with arm issues he allowed five runs with three strikeouts.

[59] In his five major league seasons he was 3-2 with two saves and a 3.53 ERA in 49 games covering 51 innings, with a 52.6% ground ball rate.

[69] He was credited with a hold during the first game of the qualifying round, striking out the final batter for Great Britain in the eighth inning of a 5–2 Israel victory.