Ryesgade is a street straddling the border of the Nørrebro and Østerbro districts of Copenhagen, Denmark.

The busy artery Fredensgade and the adjacent Fredens Park, effectively separates the Nørrebro and Østerbro portions of Ryesgade from each other.

The area between Sortedam Lake and Blegdamsvej was formerly the site of a row of narrow lots with bleaching pongs.

It served the dual purpose of dividing the long lots in two and in the same time to facilitate the construction of a new main sewer along the lakes.

The side streets are named after Hans Hedemann (Hedemannsgade), Hans Hedemann (Helgesensgade), Niels Christian Lunding (Lundingsgade), Johan Trepka (Trepkasgade), Johan Irminger (Irmingersgade), Christoph von Krogh (Kroghsgade, (Frederik Læssøe (Læssøesgade) and Frederik Adolph Schleppegrell (Schleppegrellsgade).

For many years it was therefore made up of two dead end sections, accessed from the south and north respectively.

A number of the old industrial buildings are still found in the Nørrebro section of the street.

The main wing on Ryesgade was originally a social institution, built in 1852 to a design by Niels Sigfred Nebelong.

The wing on Sankt Hans Gade and a number of smaller stable and storage buildings were added in 1971.

The building is now owned by C. W. Obel and houses creative businesses as well as Nørrebro Bryghus.

51–55 is a former machine factory, Nielsen & Winther, built in 1916 to a design by Frederik Wagner.

Most of the buildings have been demolished and replaced by the senior citizens home Sølund on the other side of the street.

[6] On the corner of Irmingergade, there is a plaque commemorating Svend Rothenberg Frederiksen, a member of the Danish resistance movement, who was shot at the site on 2 May 1945.