Fletcher was the owner and operator of his family's Cavendish farm, which included horse and cattle breeding.

During his career, Fletcher was active in the Windsor County and Vermont Agricultural Societies, and he won prizes for his horses and cows.

In addition, he was an unsuccessful candidate for various offices, including the Vermont Senate and presidential elector.

In 1854, Fletcher was the successful lieutenant governor nominee of a coalition that included the Whig, Free Soil and Liberty Parties.

He was a strong proponent of biennial rather than annual gubernatorial elections and was a tireless worker for the anti-slavery and temperance causes.

After the State House burned down in an 1857 fire, he called a special legislative session to plan for rebuilding.