Sângeorgiu de Mureș (Hungarian: Marosszentgyörgy [ˈmɒroʃsɛɲɟørɟ]) is a commune in Mureș County, Transylvania, Romania composed of three villages: Cotuș (Csejd), Sângeorgiu de Mureș, and Tofalău (Tófalva).

The commune is situated on the Transylvanian Plateau, on the left bank of the Mureș River.

It is located in the central part of the county, 7 km (4.3 mi) northeast of the county seat, Târgu Mureș, on national road DN15 [ro].

It forms part of the Târgu Mureș metropolitan area.

According to the 2011 census, it has a population of 9,304 of which 50.31% are Hungarian, 36.92% are Romanian, and 7.94% Romani.