[11] The climate in São José do Rio Preto is classified as tropical (Aw), characterized by hot and rainy summers, as well as mild and dry winters.

[11] The service sector is the main economy of São José do Rio Preto representing 84,53% of the total income and followed by the industry (15,19%).

[20] The city is home to the Diocese of São José do Rio Preto, a local heritage site situated at the same location where the first chapel was built in 1852.

The cathedral serves as the epicenter of the city and houses various artworks, including a sculpture of Saint Joseph dating back to the 19th century.

[21] According to the 2010 census, the city's population consists of the following religious affiliations: Roman Catholics (58.7%), Brazilian Protestants (23.79%), Spiritists (6.81%), individuals with no religious affiliation (5.57%), Jehovah's Witnesses (1.47%), Atheists (0.38%), members of the Church of Jesus Christ of Latter-day Saints (0.18%), Buddhists (0.18%), practitioners of Umbanda and Candomblé (0.17%), Eastern Orthodox Christians (0.07%), and Jews (0.03%).

[22] In 2018, São José do Rio Preto experienced its highest number of homicides in 16 years, with 45 recorded murders compared to 47 in 2002.

Additionally, São José do Rio Preto is known for hosting cultural events such as the International Theater Festival (FIT) and the Book Biennial (Bienal do Livro).

Presently, the park boasts over 10,000 native species of local fauna, as well as kiosks and free outdoor gym equipment.

[31] São José do Rio Preto is host to eight general medical hospitals, comprising one public, four private, and three philanthropic institutions.

[11] São José do Rio Preto is also home to two public universities: IBILCE (specializing in biosciences, languages, and exact sciences), and FATEC (which offers programs in technology).

[38] In São José do Rio Preto there are also several faculties, university centers and private universities, among them, the Centro Universitário do Norte de São Paulo - UNORTE, which is one of the most traditional in the city, founded in 1972, it is authorized by the Ministry of Education to offer undergraduate and graduate courses in all areas of knowledge, both on-site and at a distance.

private universities There are 2 companies operating the public transit system in the municipality with 230 buses on 80 different routes: Circular Santa Luzia, and Itamarati.

Three daily newspapers are circulated in São José do Rio Preto: Diário da Região and Bom Dia.

São José do Rio Preto serves as the headquarters for Rede Vida, a Brazilian broadcast television network.

[44][45] Moreover, the team actively supports alternative sports groups for individuals with disabilities, including wheelchair basketball, and swimming.

These groups consist of members from the philanthropic organization Clube Amigos dos Deficientes (Friends of the Disabled Club), who also compete at the national level.