Sätra Nature Reserve (Swedish: Sätra naturreservat) is a nature reserve in northern Uppsala County in Sweden.

Sätra Nature Reserve consists of an area of old-growth forest dominated by spruce.

A number of orchids are known to grow in the area, including Cypripedium calceolus and broad-leaved helleborine.

The nature reserve is part of the EU-wide Natura 2000-network.

This article about a location in Uppsala County, Sweden is a stub.