The Sèvre Nantaise (French pronunciation: [sɛvʁ nɑ̃tɛz]) is a river in the Pays de la Loire regions in western France.

It flows from south to north through the departments and towns listed here, reaching the river Loire in the city of Nantes.

The river is navigable over a length of 21.5 km (13.4 mi) from the village of Monnières to the confluence.

It has a horseshoe weir (Chaussée Des Moines) and lock at Vertou, and a tidal sluice open to boats an hour before and after high tide at Pont-Rousseau, in the suburbs of Nantes.

[citation needed] Its left-bank tributary the Petite Maine is also navigable over a length of 6 km (3.7 mi), up to the first disused lock and weir.