Sébastien-Melchior Cornu (6 January 1804 – 23 October 1870) was a French painter, specializing in religious works and portraits.
At the age of twelve, he began attending the École nationale supérieure des beaux-arts de Lyon.
Thanks to his wife's noble connections, he received numerous commissions from the Royal Court and the church.
His decorative work can be seen in several churches; notably Saint-Merri (1850), Saint-Séverin (1857), Saint-Roch (1859), and Saint-Germain-des-Prés (1864), where he completed a project begun by his friend, Flandrin.
His notable portraits include Alexandre Dumas, Gustave Flaubert, and George Sand.