Born in Rio Claro, Sérgio Guedes began his football career playing for Araçatuba.

Between 1984 and 1989 he played for Ponte Preta, Santos, Goiás and Cruzeiro, winning the Copa do Brasil.

In subsequent years he played for many clubs, among others, Botafogo-SP, Lousano Paulista, Santos Coritiba.

At the end of their football Sérgio Guedes was a coach.

In June 2015, hit with the Mogi Mirim in order to save lot of sticking in the Série B.