Founded by American entrepreneurs Jeff Valdez and Bruce Barshop, Sí TV was established in 1997 as a production company to develop, produce and distribute original English-language entertainment aimed primarily at a Latino audience.

When Sí TV and Galavisión parted ways in August of that year, Valdez sold the shows into national syndication in 52 markets, drawing solid ratings in New York City, Miami, Houston, and San Antonio.

[2] On March 10, 1999, Sí TV announced plans to launch the first English-language cable network aimed at young Latinos.

[1] In January 2003, it was announced that Sí TV would be launched nationally on satellite provider Dish Network at the beginning of that summer.

Valdez stated that: "For years, people have ignored the young demographic that doesn't speak Spanish but needs a voice and wants a place to call home".

[5] Sí TV's target audience of young adults aged 18–34 are "presumably those who have long since assimilated into American convention", and who "don't necessarily have any particular fealty to the sort of programming that goes to great lengths to remind them of their heritage – unlike their first-generation parents or grandparents".

Edward R. Leon, the network's senior vice president of production, assumed the additional role of acting head of programming.

Video entries were judged by the public and a panel, including CNN anchor Rick Sanchez, actress Rosario Dawson, Craigslist's Craig Newmark, former Texas congressman Henry Bonilla, YouTube's Steve Grove and Republican National Hispanic Assembly chairman Danny Vargas.

The marketplace is poised for explosive growth and the 2010 Census will validate the fact that bicultural Latinos are absolutely the fastest-growing demo in the U.S." He further stated that the job "was an opportunity he couldn’t pass up".

[9] In March 2011, the channel reached approximately 25 to 27 million households, according to its senior vice president of marketing Rafael Oller.

[10] The network expected to reach 30 million households by the end of 2011; a milestone that would make it eligible to be rated by Nielsen and would therefore be of more interest to advertisers.

[12] On September 11, NUVOtv announced a premier partnership with entertainer and entrepreneur Jennifer Lopez,[13] which would focus on appealing the network's programming to a modern, Latino audience that is "growing rapidly and in need of new, high-quality content".

"[17][18] In 2015, it was announced that NuvoTV would fold into Fuse, as the latter network expands its programming to target an audience dubbed "New Young Americans".