Søren Rasmussen started playing handball in Balling Volling Ungdoms- og Idrætsforening and switched to Hjorshøj-Egaa when he became a senior player.

The following season he signed for Flensburg-Handewitt who were looking to replace Johan Sjöstrand who had transferred to FC Barcelona Handbol.

[3] After his playing career he became a goalkeeping coach at the Danish club TTH Holstebro.

[3] Rasmussen made his debut on the national team in 2000, but it was not until the 2011 World Men's Handball Championship in Sweden, that he played at a major international tournament.

The retirement of first choice keeper Kasper Hvidt opened the door for Rasmussens spot.