Mari Jo (Maria Jose), Mariana, and her two half sisters: Cecilia and Renata, seek to survive their family problems, trying to share a father, all four being daughters of different mothers, Harriet and Laura respectively, both of whom are good women, but who share very different points of views, for reasons of generation and personality.
That person is Nelly, the jealous cousin of the girls, who together with her mother, Carmen, and the main villain, Carlos, will make life difficult for the rest, engaging in piracy.
Ernesto, the father of the sisters, is the director of a major label, he is desolated after realizing it was not true that Harriet, his first wife, betrayed him, and after 20 years he found out the lies Angustias, his former mother in law, created.
But things will not be easy for Cuco because Michelangelo, the right hand of piracy czar Carlos, will want to possess Cecilia at all costs.
Ernesto, determined that his four daughters get along, suggested that he would live alone with the four girls, creating sentimental, emotional, and comedic situations for the soap opera.