On May 6, 1993, the airport was named after the Lithuanian pilots Steponas Darius and Stasys Girėnas, who perished in a crash near the end of an attempted non-stop flight from New York to Lithuania in 1933.

During the Interwar period, when Kaunas was Lithuania's capital, Aleksotas Airport was used as the primary base of the Lithuanian Air Force.

On June 22, 1941, Luftwaffe on the ground destroyed most of the Red Army aircraft, stationed at Aleksotas Airfield.

For Autumn season, an extension to Helsinki was planned; however, it did not happen due to the outbreak of World War II.

The planes were registered LY-SOA and LY-SOB and, commemorating the national trans-Atlantic heroes, were respectively named "Steponas Darius" and "Stasys Girėnas".

The first Lithuanian civil airline was inaugurated on 5 September 1938 with domestic flights from Kaunas (the country's provisional capital at that time) to the coastal resort of Palanga.

Civil flights to Moscow were launched at the end of 1940 after the formal integration of Lithuania into the Soviet Union.

After the withdrawal of the Russian Air Force in 1993, Aleksotas / S. Darius and S. Girėnas Airport began to serve general aviation.