[2] Recognized as a global business and technology thought leader, he was voted the top CEO (IT Services category) in Institutional Investor's inaugural ranking of Asia's Top Executives and selected as one of the winners of the second Asian Corporate Director Recognition Awards by Corporate Governance Asia in 2011.

As per Forbes list of India’s 100 richest tycoons, dated OCTOBER 09, 2024, Senapathy Gopalakrishnan is ranked 73rd with a net worth of $4.35 Billion.

He has used some of his wealth - as of May 30, 2023, according to Forbes, estimated at $2.9 billion, towards causes such as health research, specifically brain science as well as technology-driven innovation that has a direct impact on society.

[21] He has contributed an additional ₹60 crores to set up distinguished visiting chairs in Neurocomputing and Data Science at the IISc Bengaluru and Indian Institute of Technology Madras of Chennai.

[28] He is also supporting the Accelerator Program for Discovery in Brain Disorders using Stem Cells at the National Centre for Biological Sciences in Bangalore, Karnataka.

He is on the Board of Swasth Digital Health Foundation, a not-for-profit consortium charting an innovative healthcare model in India.

[31][32] Kris established the Gopalakrishnan – Deshpande Centre for Innovation and Entrepreneurship at IIT Madras in August 2017, to be able to solve India's society's problems by applying the full capabilities of the scientific and technological knowledge of Indian academic institutions through world class innovation and entrepreneurship.