SARS-CoV-2 Zeta variant

It evolved independently in Rio de Janeiro without being directly related to the Gamma variant from Manaus.

[3] A second wave was preceded in November 2020 by an increase in the prevalence of the Zeta variant among genetic sequences from São Paulo state, deposited into the GISAID database.

[4] As of July 2021, Zeta is no longer considered a variant of interest by the WHO.

[5] The Zeta genome has 3 amino acid mutations: E484K, D614G, and V1176F, all of which are found in the virus's spike protein code.

[6] According to the Centers for Disease Control and Prevention, F565L has been detected in some of the Zeta variant sequences, but not all.