KMT5A

1ZKK, 2BQZ, 3F9W, 3F9X, 3F9Y, 3F9Z, 4IJ8, 5HQ238789367956ENSG00000183955ENSMUSG00000049327Q9NQR1Q2YDW7NM_001367388NM_001367389NM_030241NM_001310723NM_001310725NM_001310727NP_001354317NP_001354318NP_001392319N-lysine methyltransferase KMT5A is an enzyme that in humans is encoded by the KMT5A gene.

[5][6][7][8] The enzyme is a histone methyltransferase, SET domain-containing and lysine-specific.

The enzyme transfers one methyl group to histone H4 lysine residue at position 20.

S-Adenosyl methionine (SAM) is both the cofactor and the methyl group donor.

This article on a gene on human chromosome 12 is a stub.

Leftmost: side chain of lysine. Next: N 6 -methyllysine side chain.