357110380ENSG00000146950ENSMUSG00000045180Q13796A2ALU4NM_001649NM_001320663NM_001320664NM_001359158NM_001359161NM_001359163NP_001307592NP_001307593NP_001640NP_001346087NP_001346090NP_001346092Shroom family member 2 is a protein that in humans is encoded by the SHROOM2 gene.

[5] This gene represents the human homolog of Xenopus laevis apical protein (APX) gene, which is implicated in amiloride-sensitive sodium channel activity.

Depletion of this gene results in an increase in endothelial sprouting, migration, and angiogenesis.

This gene is highly expressed in the retina, and is a strong candidate for ocular albinism type 1 syndrome.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.