SMAP×SMAP, often referred to simply as Sma-Sma, was a Japanese television variety show hosted by boy band SMAP.

It quickly became the most watched television program, attracting an average of 20 million viewers per episode, often ranking at #1 in year-end ratings.

SMAPxSMAP was launched six months after Gambarimashou ended and became the band's first television program on a prime-time slot.

International guests include: Will Smith, Brad Pitt, Robert De Niro, Tom Hanks, Hugh Jackman, Richard Gere, Harrison Ford, Nicolas Cage, Arnold Schwarzenegger, Denzel Washington, Whoopi Goldberg, Cameron Diaz, Paris Hilton, Jane Birkin, Amanda Seyfried, Miranda Kerr, Steven Spielberg, Quentin Tarantino, David Beckham, Neymar, Usain Bolt, Mikhail Gorbachev, etc.

On episodes they do not have a musical guest, The End Talk is done by the band alone and the length of the segment is longer than usual, often answering questions from the fans they get through the program's website.

International guests include: Michael Jackson, Bon Jovi, James Brown, Stevie Wonder, Justin Bieber, Backstreet Boys, The Black Eyed Peas, Maroon 5, Earth, Wind & Fire, Lady Gaga, Beyoncé, Taylor Swift, Ariana Grande, Mariah Carey, Katy Perry, etc.

The last episode of the series features clips from the show's twenty-year run aired on December 26, 2016 at 18:30 JST After Inagaki's temporary hiatus in 2001, SMAP made their first television appearance as a five-piece for the first time in six months.

During the taping of the program's musical segment, S-Live, Jackson appeared on the set and visited SMAP.

The episode also aired footage of Jackson watching the band's performance in the production control room backstage, before he made his appearance on the set.

Jackson promised SMAP that he would make an official guest appearance on the program the next time he was in Japan, though that did not come true, due to his death in 2009.

On April 8, 2013, a three-hour-long special entitled, SMAP's First Trip aired in celebration of the band's 25th anniversary since its formation in 1988.

The band was given a three-day break to take a trip as a group, without an itinerary, allowing the members to do whatever they wanted.

The band performed all of their past fifty singles in a medley, nonstop for forty minutes, without a break and without any commercials.

Baby Smap is a five-minute-long spin-off or sidequel of SMAPxSMAP that has been airing on Sunday nights at 1:30 a.m. from April 15, 2007.

Occasionally, the program is subtitled "New Project Factory" and SMAP members appear on the show, participating in the taping of short games.

It was originally created to let young, rookie or "baby" television producers come up with ideas for a new segment for SMAPxSMAP.