[1][Note 1] In an eight-month career, the UC-29 performed seven combat patrols into the Atlantic Ocean during the German war on Allied trade (Handelskrieg).

On 7 June 1917 she torpedoed the British Q-ship HMS Pargust off the Irish coast, but was ambushed by her hidden armaments when she approached too close and was sunk with 23 hands.

She had a dive time of 48 seconds and was capable of operating at a depth of 50 metres (160 ft).

When submerged, she could operate for 53 nautical miles (98 km; 61 mi) at 4 knots (7.4 km/h; 4.6 mph); when surfaced, she could travel 9,410 nautical miles (17,430 km; 10,830 mi) at 7 knots (13 km/h; 8.1 mph).

UC-29 was fitted with six 100 centimetres (39 in) mine tubes, eighteen UC 200 mines, three 50 centimetres (20 in) torpedo tubes (one on the stern and two on the bow), seven torpedoes, and one 8.8 cm (3.5 in) Uk L/30 deck gun.