Known for most of its length as Rogers Clark Boulevard, the state highway runs 11.93 miles (19.20 km) from U.S. Route 1 (US 1) in Ruther Glen east to US 301 and SR 2 in Bowling Green.

SR 207 begins at an intersection with US 1 (Emancipation Highway) in Ruther Glen, in an area also known as Carmel Church, in western Caroline County.

The route was enlarged by 1937 with the addition of a second section running from a point 2 miles (3.2 km) east of Bowling Green through Port Royal to an intersection with SR 3 at Office Hall.

The two-lane highway, which has a length of 1.27 miles (2.04 km), begins at SR 207, which heads west as Rogers Clark Boulevard and east as the Bowling Green Bypass.

SR 207 Business heads northeast as Rogers Clark Boulevard and becomes Broaddus Avenue on entering the town limits of Bowling Green.

US 301 Business also heads south on Main Street and east on Broaddus Avenue to its northern end between Bowling Green and Fort A.P.