SS Melville E. Stone was a Liberty ship built in the United States during World War II.

She was named after Melville Elijah Stone (August 22, 1848 – February 15, 1929), a newspaper publisher, founder of the Chicago Daily News, and one time general manager of the reorganized Associated Press.

[2] The ship's keel was laid in Permanente Metals Richmond, California, Yard 2 on July 2, 1943 as hull number 1715, type EC2-S-C1.

[3] At 06:14 hours on November 24, 1943, the unescorted Melville E. Stone was hit by two torpedoes from the German submarine U-516 about 100 miles (160 km) northwest of Cristóbal, Canal Zone, at 10°29′N 80°20′W / 10.483°N 80.333°W / 10.483; -80.333.

Two of the lifeboats capsized from the suction created by the ship, which sank within eight minutes and several men drowned, including the master.