SS William Gaston (MC contract 159) was a Liberty ship built in the United States during World War II.

The ship was laid down by North Carolina Shipbuilding Company in their Cape Fear River yard on May 23, 1942, then launched on July 19, 1942.

[1] She was operated by the American West Africa Line for the War Shipping Administration.

[2] On July 23, 1944 while traveling between Buenos Aires, Argentina and Baltimore, Maryland Gaston was torpedoed by the German submarine U-861.

Gaston rolled over and sank three minutes after the second torpedo without loss of life.