Right after graduating from the Lyceum, she worked for some time as a teacher in the normal girls' school in the city, teaching the subjects of Moral Education and French Language.

The Albanian state awarded her a scholarship to the University of Turin, at the Faculty of Biological Sciences, which she successfully completed with full and excellent grades.

[4][5] Upon returning to her homeland, Kasimati was appointed a teacher at the Women's Institute "Nana Mbretëreshë", which after the Italian occupation was named "Donika Kastrioti".

For health reasons she was forced to leave her pedagogical work and be treated at the anti-tuberculosis sanatorium in northern Italy in Bolzano, where she remained until 1945.

[7] Kasimati managed to write a long programmatic article entitled "Problems of fish and fisheries in our country", published in the Bulletin of the Institute in No.

[8] In that long technical-scientific article, she treated analytically the ichthyological wealth of the country, according to the areas, the problems of breeding and necessary cultivation of some species, especially carp, koran, European bass, etc.

[5][9] According to the data of her study, in these areas are found mostly high-quality fish, such as Sturgeon, European bass, Twait shad, Orata, and Eel.

In order to convince the public and economists it analyzes and offers some suggestions where the state can benefit from fisheries, including newly formed cooperatives.

A negative phenomenon that Kasimati had ascertained, was the indiscriminate, very intensive exploitation of fish with high commercial values and consequently, the impoverishment of ichthyofauna with these species.

[7][3] In 1949, the Department of Natural Sciences carried out a long study expedition in the areas of Kukës, Bicaj, Pukë, Burrel, Qafë-Shtamë; Bogë, and Theth, thus realizing a verification of previous findings regarding the ichthyofauna of Albanian waters.

[11] Kasimati had long opposed many of the policies of the post-war communist regime, especially after the elimination and internment of some Albanian intellectuals, who often had nothing to do with the political opponents of the PPSH.

On March 5, the then Minister of Justice, Manol Konomi, was fired for disagreeing with the violation of legality and the fabrication of a trial that had not previously taken place for those 22 people already killed.