[1] Lane was born in Melbourne, Victoria and grew up the regional city of Mildura where she attended Catholic school St Joseph's College.

[3] Lane returned to the ABC in 2006 to work for the network's radio current affairs department after studying an audio engineering course at night school.

[1] In 2008, she moved to Canberra to work as a reporter in the press gallery at Parliament House, covering federal politics for ABC programs AM, The World Today and PM, during which time she was promoted to chief radio current affairs correspondent.

[8][9] She received praise in 2019 for her raw emotional response live on air immediately following the broadcast of a story by foreign correspondent Samantha Hawley about a Ukrainian girl who was allegedly abandoned by her American surrogate parents.

[12] Lane has listed her two most memorable interviews from her career to date as being the ones she conducted with Barry Cohen about his struggle with Alzheimer's disease, and with Craig Laundy about his push for a change in government policy to enable more refugees into Australia.

"[2] As a teenager, Lane was diagnosed with polycystic ovary syndrome and was incorrectly told by a doctor that she would be unable to have children despite many women being able to do so with the help of fertility treatment, a fact that she didn't learn until much later in life.