Established in 1925, Sagamore Farm was owned by Isaac Edward Emerson of Baltimore, who assembled the property as a gift for his daughter, Margaret.

In 1941, Vanderbilt teamed up with Walter P. Chrysler Jr. and other investors to acquire for breeding services the 1935 English Triple Crown winner Bahram from the Aga Khan III.

In 1966, Vanderbilt was part of another syndicate that bought Kentucky Derby and Preakness Stakes winner Kauai King who would also stand at stud at Sagamore Farm.

In 2007 Maryland native Kevin Plank, CEO of Under Armour apparel company, bought the farm with a long-term plan for a major restoration.

On November 5, 2010, a Sagamore Farm owned racemare named Shared Account won the $2 million Breeders' Cup Filly & Mare Turf.