Having fled his native Burundi as a child, he received political asylum in Birmingham and credits football with helping him integrate into English society.

Berahino made his first starts for West Bromwich Albion in the 2013–14 season, with highlights of that campaign including a hat-trick against Newport County and the winning goal at Old Trafford against Manchester United.

[5] He travelled to England alone at the age of 10,[6][7] fleeing the ongoing war to join his mother, brother and sisters who had already been granted asylum in Newtown, Birmingham.

[4] Berahino attended Aston Manor School,[8] where he gained ten GCSE certificates and competed in basketball and athletics in addition to football.

[9] Initially speaking only French[10] and having played street football in his native Burundi, Berahino attributed his love for the sport with helping him integrate quickly into English society.

[6] Berahino signed for the West Bromwich Albion Centre of Excellence in 2004 at under-12 level, joining from inner-city youth club Phoenix United.

"[22] Due to arguments with new manager Uwe Rösler, the loan spell with Brentford ended early and he returned to West Bromwich Albion on 3 April, having scored 4 goals in 8 appearances.

[23] Berahino made his debut for West Brom as a substitute against Yeovil Town in a League Cup second round tie on 28 August 2012, replacing Shane Long for the final six minutes of a 4–2 away win.

[29] At the start of the 2013–14 season, manager Steve Clarke suggested that Berahino should become West Bromwich Albion's main centre forward, instead of the club signing a new one.

[30] He made his first league appearance for the Baggies when he came on as a substitute in a 2–0 home defeat against Swansea City on 1 September 2013, replacing Scott Sinclair for the last 15 minutes of the match.

[36] His good start to the season prompted the club to consider a new contract worth over £50,000 per week, but discussion of it was put on hold in late November due to his arrest on suspicion of drink driving.

[42] Three days later, he scored the team's final goal in a 4–0 defeat of West Ham United to put the Baggies into the quarter-finals of the FA Cup for the first time since 2008.

[63] On 23 August, he missed from the penalty spot as West Bromwich Albion lost on a shootout away to his former team Northampton, in the first round of the EFL Cup.

[64] In November, Berahino was assigned extra work in training and sent to a camp in France after he was found to be 8 pounds overweight by West Brom's medical staff.

He said in an open statement on the team's website that constant speculation had made it the "most difficult year" of his career, causing him to "feel depressed" and affect his fitness.

[69] Manager Mark Hughes revealed that Berahino had served an eight-week suspension by the FA during his time at West Brom after failing an out-of-competition drugs test.

[75][76] On 30 September 2017, in his 31st consecutive career game without a goal, Berahino won a penalty when fouled by Southampton's Virgil van Dijk and took it himself, but Fraser Forster saved it.

[80] Berahino continued to struggle in 2017–18 and with the team in deep relegation trouble in April and Hughes having been sacked in January, he was banished to the under-23s by new manager Paul Lambert due to poor discipline.

"[95] Another former Stoke teammate, Peter Crouch, also spoke out about the situation, saying "I'm not going to say Glen was wrong (about Berahino), but there were many players in that dressing room who didn't pull their weight, not just him.

[99] On 31 August 2021, Berahino returned to England to join League One club Sheffield Wednesday having previously worked with Owls manager Darren Moore at West Brom.

[100] He made his debut on 11 September as a 58th-minute substitute in a 3–0 loss away to Plymouth Argyle[101] and scored his first goal for the club a week later, opening a 1–1 home draw against Shrewsbury Town.

Berahino, whose form was described as "hit and miss" by local newspaper The Star, said he needed two months in the gym to compete physically in England's third tier.

[116] Berahino was yellow-carded after the first of his two goals in a 3–0 win against Finland under-21 in a European qualifier on 15 November 2013, for lifting his shirt to reveal a message to his late father, who died in the Burundian Civil War.

Berahino was named in the England under-21 squad for 2015 UEFA European Under-21 Championship in the Czech Republic[121] but withdrew through injury on 18 June, to be replaced by Benik Afobe.

[128] In October 2013, Berahino told The Daily Telegraph that the strikers he aims to emulate are Samuel Eto'o, Didier Drogba and Jermain Defoe "because of their movement and the way they finish".

[5] When interviewed by BBC Sport in February 2015, West Bromwich Albion manager Tony Pulis said that Berahino could be a "top-class player" but needed "direction".

[129] Berahino's England under-21 manager Gareth Southgate said that he has an ability to create space on the pitch for his teammates and became physically and mentally stronger since they began working together.

West Bromwich Albion goalkeeper Ben Foster stated that Berahino was more committed in training than other players of his age and followed a healthy diet.

[11] His former West Bromwich Albion teammate Steven Reid said that Berahino's attitude to training improved as a result of dealing with two "turning points", namely his expulsion from Brentford and knee injury at Peterborough.

[5] In April 2014, Berahino apologised to West Bromwich Albion after videos of him inhaling nitrous oxide for recreational purposes were discovered by the media.