In their inaugural season, the club achieved promotion to top flight as the runners-up of 2016 Bangladesh Championship League.

The club also provided seven of their local players – Sazzad, Kabir, Shadin, Saddam, Rafi, Likhon and Rahim – four-year contracts.

Pinning down such number of players to long-term contracts is an unusual scene in the country's domestic football scenario.

The club also signed national booters Shakil Ahmed, Hemanta Vincent Biswas, Jewel Rana, Ariful Islam and Topu Barman, who was paid the highest.

Saif Sporting's foreign signings include forwards Hember Valencia, Alvi Fokou Fopa and midfielder Deiner Córdoba.

[20] Saif SC started their 2017 Bangladesh Federation Cup journey with 1–1 goal draw against defending champion Dhaka Abahani.

On 28 July 2017, Saif Sporting Club played their first professional league game against Dhaka Abahani where they lost the match by a 3–2 margin.

[23][24] On 26 August 2017, Colombian forward Hember Valencia scored the club's first ever hat-trick, as Saif trashed Brothers Union 5–0 during 2017 Bangladesh Premier League.

[26][27] Saif Sporting Club played their first match against Dhaka Abahani on 13 November 2017 under the guidance of their new head coach Ryan Northmore and were victorious by 2–1 margin.

[28] New foreign recruit Wedson Anselme and Charlie Sheringham both of them scored one goal each in this match for the club on their debut.

[29][30] On 2 January 2018, history was created as Saif Sporting Club beat Sheikh Russel KC 2–1 to qualify for the 2018 AFC Cup playoffs after confirming at least a fourth-place finish in the Bangladesh Premier League and they did it on their professional debut and in just two seasons of emergence.

Due to poor performance in both domestic and continental circuit Head Coach Ryan Northmore was sacked from the club at end of the season.

[37] On 1 August 2018, club signed South Korean forward Park Seung-il as their first ever Asian visa foreigner for upcoming league.

[38] On 23 September 2018, Saif SC clinched the Bodousa Cup title with a 2–0 win over ISL side Jamshedpur FC Reserves in the final at Katchujan Field, Tinsukia.

[42] Eventually they lost the game by 2-1 goals and were out of the tournament with McKinstry watching from the stands as Assistant Coach Dennis Kitambi was placed in charge of the team on an interim basis.

[45] On 19 January 2019, Saif Sporting Club were off to a winning start in the Bangladesh Premier League 2018–19 season as they handed Rahmatganj MFS a 2–1 defeat at Rafiq Uddin Bhuiyan Stadium in Mymensingh.

[46] On 6 April 2019, Saif Sporting Club defeated NoFeL SC 1–0 in the Bangladesh Premier League 2018–19 with a goal from Park Seung-il.

On 7 November, Saif Sporting appointed Maldivian Mohamed Nizam as the new head coach ahead of the upcoming football season 2019–20.

[53] Saif reached their first-ever Federation Cup final on 6 January 2021, thrashing former finalist Chittagong Abahani by 3-0 goals.

[56] On 24 March 2022, the clubs Managing Director Nasiruddin Chowdhury and General Secretary Mahbubur Rahman Sumon announced their resignation.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.