Saint-Aignan-Grandlieu (French pronunciation: [sɛ̃t‿ɛɲɑ̃ ɡʁɑ̃ljø] ⓘ; Breton: Sant-Enion-al-Lenn-Veur; Gallo: Saent-Aenyan-Graund-Loe) is a commune in the Loire-Atlantique department in the administrative region of Pays de la Loire, France.

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