Saint-Alphonse (French pronunciation: [sɛ̃t‿alfɔ̃s]) is a municipality in Quebec, Canada.

They founded the parish of Saint-Alphonse-de-Liguori in 1891, named after Alphonsus Liguori since Mussely was a Redemptorist.

The place was originally known as La Petite-Belgique (French for "Little Belgium"), but the Belgian families did not remain long due to the harsh climate and short growing season, replaced by people from around Chaleur Bay.

The following year, the Municipality of Musselyville was created out of territory ceded by Township of New Richmond and the Parish Municipality of Saint-Bonaventure de Hamilton.

[1][4] On October 24, 1953, the municipality changed its name from Musselyville to Saint-Alphonse.