Saint-Cyprien (French pronunciation: [sɛ̃ sipʁijɛ̃] ⓘ) is a parish in the Les Etchemins Regional County Municipality in Quebec, Canada.

It is part of the Chaudière-Appalaches region and the population is 490 as of 2016.

It is named after Christian martyr Cyprian.

Saint-Cyprien lies on the Canada–United States border.

[4] Population trend:[5] The South Shore Protestant Regional School Board previously served the municipality.