[1] Saint-Dizier has a long aviation history, with an early French military aircraft landing close to the city on 11 August 1910.

Some of the pre-World War II French Air Force aircraft assigned to the base were Blériot Aéronautique, Morane-Saulnier, Stampe, de Havilland Tiger Moth and Dewoitine D.520s[4] Seized by the Germans in June 1940 during the Battle of France, St. Dizier was used as a Luftwaffe military airfield during the occupation.

Largely due to its use as a base for Bf 109 interceptors, Saint-Dizier was attacked by USAAF Ninth Air Force Martin B-26 Marauder medium bombers and Republic P-47 Thunderbolts mostly with 500-pound general-purpose bombs; unguided rockets and .50 caliber machine gun sweeps when Eighth Air Force heavy bombers (Boeing B-17 Flying Fortresses, Consolidated B-24 Liberators) were within interception range of the Luftwaffe aircraft assigned to the base.

The IX Engineer Command repaired the war-damaged base and it was designated by the Americans as Saint-Dizier Airfield or Advanced Landing Ground A-64.

Right after the war, some captured Messerschmitt Me 262s landed at the base, on their way to channel ports to be shipped to the United States for evaluation (Operation Lusty).

[9] The war had left Saint-Dizier airbase in ruins, littered with rubble, debris, scrap metal and charred remains of airplanes.

The station area and the hangars and aircraft mechanical shops were devastated, also with huge quantities of unexploded munitions still littering the ground.